EMD 534085 from Cayman Chemical

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EMD 534085

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Description

An Eg5 inhibitor (IC50 = 8 nM); inhibits proliferation of HCT116 cells (IC50 = 30 nM); induces mitotic arrest and apoptosis in HL-60 cells; reduces tumor growth in a COLO 205 colon cancer mouse xenograft model at 15 and 30 mg/kg